Structure of PDB 5sw9 Chain A Binding Site BS01

Receptor Information
>5sw9 Chain A (length=324) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ADQEKLFIQKLRQCCVLFDFVSDPLSDLKWKEVKRAALSEMVEYITHNRN
VITEPIYPEVVHMFAVNMFRTLPPEAAWPHLQLVYEFFLRFLESPDFQPN
IAKKYIDQKFVLQLLELFDSEDPRERDFLKTTLHRIYGKFLGLRAYIRKQ
INNIFYRFIYETEHHNGIAELLEILGSIINGFALPLKEEHKIFLLKVLLP
LHKVKSLSVYHPQLAYCVVQFLEKDSTLTEPVVMALLKYWPKTHSPKEVM
FLNELEEILDVIEPSEFVKIMEPLFRQLAKCVSSPHFQVAERALYYWNNE
YIMSLISDNAAKILPIMFPSLYRN
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5sw9 Expanding the PP2A Interactome by Defining a B56-Specific SLiM.
Resolution2.846 Å
Binding residue
(original residue number in PDB)		H187 R188 Y190 L194 R197 R201 S230 N233 G234 F235 A236 H243
Binding residue
(residue number reindexed from 1)		H134 R135 Y137 L141 R144 R148 S177 N180 G181 F182 A183 H190
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019888 protein phosphatase regulator activity
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0000159 protein phosphatase type 2A complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5sw9, PDBe:5sw9, PDBj:5sw9
PDBsum5sw9
PubMed27998540
UniProtQ13362|2A5G_HUMAN Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (Gene Name=PPP2R5C)

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