Structure of PDB 5sup Chain A Binding Site BS01

Receptor Information
>5sup Chain A (length=383) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TGFKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLG
KTAVFVLSTLQQLDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVK
TAVFYGGTPISKDAELLKNKDTAPHIVVATPGRLKALVREKYIDLSHVKN
FVIDECDKVLEELDMRRDVQEIFRATPRDKQVMMFSATLSQEIRPICRRF
LQNPLEIFVDDEAKLTLHGLQQYYIKLEEREKNRKLAQLLDDLEFNQVII
FVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICV
STDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVS
SKEDEEVLAKIQERFDVKIAEFPEEGIDPSTYL
Ligand information
>5sup Chain H (length=17) Species: 559292 (Saccharomyces cerevisiae S288C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AKKSLEDLDKEMADYFE
Receptor-Ligand Complex Structure
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PDB5sup Structural and biochemical analyses of the DEAD-box ATPase Sub2 in association with THO or Yra1.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		R227 R228 Q231 F234 R235 T237 P238 R239 R260 F261 Q263
Binding residue
(residue number reindexed from 1)		R166 R167 Q170 F173 R174 T176 P177 R178 R199 F200 Q202
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003724 RNA helicase activity
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:5sup, PDBe:5sup, PDBj:5sup
PDBsum5sup
PubMed28059701
UniProtQ07478|SUB2_YEAST ATP-dependent RNA helicase SUB2 (Gene Name=SUB2)

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