Structure of PDB 5s8c Chain A Binding Site BS01

Receptor Information
>5s8c Chain A (length=118) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFAT
VRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFE
EHISSVLSDYKSALRFHK
Ligand information
Ligand IDRYD
InChIInChI=1S/C8H9N3O/c1-11-8-3-2-6(5-12)4-7(8)9-10-11/h2-4,12H,5H2,1H3
InChIKeyHVLCKOBNGNRDPT-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385Cn1nnc2cc(CO)ccc12
OpenEye OEToolkits 2.0.6Cn1c2ccc(cc2nn1)CO
FormulaC8 H9 N3 O
Name(1-methylbenzotriazol-5-yl)methanol
ChEMBL
DrugBank
ZINCZINC000000158987
PDB chain5s8c Chain A Residue 1501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5s8c XChem group deposition
Resolution1.25 Å
Binding residue
(original residue number in PDB)		Y1350 S1392 Y1395 P1397 S1401 I1403
Binding residue
(residue number reindexed from 1)		Y35 S77 Y80 P82 S86 I88
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5s8c, PDBe:5s8c, PDBj:5s8c
PDBsum5s8c
PubMed
UniProtQ8WWQ0|PHIP_HUMAN PH-interacting protein (Gene Name=PHIP)

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