Structure of PDB 5r4j Chain A Binding Site BS01

Receptor Information
>5r4j Chain A (length=119) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EDAMTVLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPVDPNDAPDYYGVI
KEPMDLATMEERVQRRYYEKLTEFVADMTKIFDNCRYYNPSDSPFYQCAE
VLESFFVQKLKGFKASRSH
Ligand information
Ligand IDRUY
InChIInChI=1S/C7H12N4O/c8-6-7(10-12-9-6)11-4-2-1-3-5-11/h1-5H2,(H2,8,9)
InChIKeyRVSIGDHRHURXCQ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.6C1CCN(CC1)c2c(non2)N
CACTVS 3.385Nc1nonc1N2CCCCC2
ACDLabs 12.01N2(c1nonc1N)CCCCC2
FormulaC7 H12 N4 O
Name4-(piperidin-1-yl)-1,2,5-oxadiazol-3-amine
ChEMBLCHEMBL1330631
DrugBank
ZINCZINC000000322796
PDB chain5r4j Chain A Residue 3003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5r4j PanDDA analysis group deposition
Resolution1.39 Å
Binding residue
(original residue number in PDB)		A2835 Y2880 N2881 F2887
Binding residue
(residue number reindexed from 1)		A43 Y88 N89 F95
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
Cellular Component
GO:0016589 NURF complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5r4j, PDBe:5r4j, PDBj:5r4j
PDBsum5r4j
PubMed
UniProtQ12830|BPTF_HUMAN Nucleosome-remodeling factor subunit BPTF (Gene Name=BPTF)

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