Structure of PDB 5pba Chain A Binding Site BS01

Receptor Information
>5pba Chain A (length=115) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMSVKKPKRDDSKDLALCSMILTEMETHEDAWPFLLPVNLKLVPGYKKVI
KKPMDFSTIREKLSSGQYPNLETFALDVRLVFDNCETFNEDDSDIGRAGH
NMRKYFEKKWTDTFK
Ligand information
Ligand ID53B
InChIInChI=1S/C6H5NO3/c8-5-3-1-2-4(7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)
InChIKeyVRCWSYYXUCKEED-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.385OC(=O)c1cccc(O)n1
ACDLabs 12.01c1cc(nc(c1)C(=O)O)O
OpenEye OEToolkits 1.9.2c1cc(nc(c1)O)C(=O)O
FormulaC6 H5 N O3
Name6-hydroxypyridine-2-carboxylic acid
ChEMBLCHEMBL1650602
DrugBank
ZINCZINC000000156920
PDB chain5pba Chain A Residue 2003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5pba A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Resolution1.925 Å
Binding residue
(original residue number in PDB)		F1943 N1944 I1950
Binding residue
(residue number reindexed from 1)		F88 N89 I95
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5pba, PDBe:5pba, PDBj:5pba
PDBsum5pba
PubMed28436492
UniProtQ9UIF8|BAZ2B_HUMAN Bromodomain adjacent to zinc finger domain protein 2B (Gene Name=BAZ2B)

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