Structure of PDB 5pad Chain A Binding Site BS01

Receptor Information
>5pad Chain A (length=212) Species: 3649 (Carica papaya) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNQYSE
QELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREK
GPYAAKTDGVRQVQPYNQGALLYSIANQPVSVVLQAAGKDFQLYRGGIFV
GPCGNKVDHAVAAVGYGPNYILIKNSWGTGWGENGYIRIKRGTGNSYGVC
GLYTSSFYPVKN
Ligand information
Receptor-Ligand Complex Structure
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PDB5pad Binding of chloromethyl ketone substrate analogues to crystalline papain.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		G23 C25 Y61 G65 G66 Y67 V133 V157 D158
Binding residue
(residue number reindexed from 1)		G23 C25 Y61 G65 G66 Y67 V133 V157 D158
Enzymatic activity
Catalytic site (original residue number in PDB) V16 Q19 C25 N155 H159 N175
Catalytic site (residue number reindexed from 1) V16 Q19 C25 N155 H159 N175
Enzyme Commision number 3.4.22.2: papain.
Gene Ontology
Molecular Function
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5pad, PDBe:5pad, PDBj:5pad
PDBsum5pad
PubMed952885
UniProtP00784|PAPA1_CARPA Papain

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