Structure of PDB 5ox2 Chain A Binding Site BS01

Receptor Information
>5ox2 Chain A (length=266) Species: 1390 (Bacillus amyloliquefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKCVSYGVAQIKAPALHSQGYTGSNVKVAVLDSGIDSSHPDLNVAGGASF
VPSETNPFQDNNSHGTHVAGTVLAVAPSASLYAVKVLGADGSGQYSWIIN
GIEWAIANNMDVINMSLGGPSGSAALKAAVDKAVASGVVVVAAAGNNGTS
GSSSTVDYPAKYPSVIAVGAVDSSNQRAPWSSVGPELDVMAPGVSICSTL
PGGKYGARSGTCGASNHVAGAAALILSKHPNWTNTQVRSSLENTATKLGD
SFYYGKGLINVEAAAQ
Ligand information
>5ox2 Chain P (length=9) Species: 1390 (Bacillus amyloliquefaciens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
VEEDHVAHA
Receptor-Ligand Complex Structure
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PDB5ox2 Design of a substrate-tailored peptiligase variant for the efficient synthesis of thymosin-alpha1.
Resolution2.24 Å
Binding residue
(original residue number in PDB)		H64 G100 S101 G102 Q103 Y104 S105 L126 G127 S130 G131
Binding residue
(residue number reindexed from 1)		H64 G91 S92 G93 Q94 Y95 S96 L117 G118 S121 G122
Enzymatic activity
Enzyme Commision number 3.4.21.62: subtilisin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5ox2, PDBe:5ox2, PDBj:5ox2
PDBsum5ox2
PubMed29300408
UniProtP00782|SUBT_BACAM Subtilisin BPN' (Gene Name=apr)

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