Structure of PDB 5owb Chain A Binding Site BS01

Receptor Information
>5owb Chain A (length=112) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQLTPFLILLRKTLEQLQEKDTGNIFSEPVPLSEVPDYLDHIKKPMDFFT
MKQNLEAYRYLNFDDFEEDFNLIVSNCLKYNAKDTIFYRAAVRLREQGGA
VLRQARRQAEKM
Ligand information
Ligand IDAYW
InChIInChI=1S/C9H8O3/c1-5-2-6(10)3-8-9(5)7(11)4-12-8/h2-3,10H,4H2,1H3
InChIKeyJANZWCJQQFVOPT-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.6Cc1cc(cc2c1C(=O)CO2)O
CACTVS 3.385Cc1cc(O)cc2OCC(=O)c12
FormulaC9 H8 O3
Name4-methyl-6-oxidanyl-1-benzofuran-3-one
ChEMBL
DrugBank
ZINCZINC000006760790
PDB chain5owb Chain A Residue 802 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5owb Crystal structure of the human BRPF1 bromodomain in complex with DSPBP1004
Resolution1.65 Å
Binding residue
(original residue number in PDB)		V657 P658 Y707 N708 F714
Binding residue
(residue number reindexed from 1)		V30 P31 Y80 N81 F87
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5owb, PDBe:5owb, PDBj:5owb
PDBsum5owb
PubMed
UniProtP55201|BRPF1_HUMAN Peregrin (Gene Name=BRPF1)

[Back to BioLiP]