Structure of PDB 5omv Chain A Binding Site BS01

Receptor Information
>5omv Chain A (length=758) Species: 103799 (Thermococcus sp. 9oN-7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MILDTDYITENGKPVIRVFKKENGEFKIEYDRTFEPYFYALLKDDSAIED
VKKVTAKRHGTVVKVKRAEKVQKKFLGRPIEVWKLYFNHPQDVPAIRDRI
RAHPAVVDIYEYDIPFAKRYLIDKGLIPMEGDEELTMLAFAIATLYHEGE
EFGTGPILMISYADGSEARVITWKKIDLPYVDVVSTEKEMIKRFLRVVRE
KDPDVLITYNGDNFDFAYLKKRCEELGIKFTLGRDGSEPKIQRMGDRFAV
EVKGRIHFDLYPVIRRTINLPTYTLEAVYEAVFGKPKEKVYAEEIAQAWE
SGEGLERVARYSMEDAKVTYELGREFFPMEAQLSRLIGQSLWDVSRSSTG
NLVEWFLLRKAYKRNELAPNKPDERELARRRGGYAGGYVKEPERGLWDNI
VYLDFRSLYPSIIITHNVSPDTLNREGCKEYDVAPEVGHKFCKDFPGFIP
SLLGDLLEERQKIKRKMKATVDPLEKKLLDYRQRAIKILANSFYGYYGYA
KARWYCKECAESVTAWGREYIEMVIRELEEKFGFKVLYADTDGLHATIPG
ADAETVKKKAKEFLKYINPKLPGLLELEYEGFYVRGFFVTKKKYAVIDEE
GKITTRGLEIVRRDWSEIAKETQARVLEAILKHGDVEEAVRIVKEVTEKL
SKYEVPPEKLVIHEQITRDLRDYKATGPHVAVAKRLAARGVKIRPGTVIS
YIVLKGSGRIGDRAIPADEFDPTKHRYDAEYYIENQVLPAVERILKAFGY
RKEDLRYQ
Ligand information
Receptor-Ligand Complex Structure
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PDB5omv Crystal structures of ternary complexes of archaeal B-family DNA polymerases.
Resolution2.003 Å
Binding residue
(original residue number in PDB)
D246 S348 G350 Y384 A385 G386 G387 S492 G495 G498 Y499 K501 T590 K591 K592 K593 W615 P678 R709 I710 Y731 N735 R743
Binding residue
(residue number reindexed from 1)
D246 S348 G350 Y384 A385 G386 G387 S492 G495 G498 Y499 K501 T590 K591 K592 K593 W615 P678 R709 I710 Y731 N735 R743
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0071897 DNA biosynthetic process

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Molecular Function

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Biological Process
External links
PDB RCSB:5omv, PDBe:5omv, PDBj:5omv
PDBsum5omv
PubMed29211756
UniProtQ56366|DPOL_THES9 DNA polymerase (Gene Name=pol)

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