Structure of PDB 5ojj Chain A Binding Site BS01

Receptor Information
>5ojj Chain A (length=151) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASRLKRELHMLATEPPPGITCWQDKDQMDDLRAQILGGANTPYEKGVFKL
EVIIPERYPFEPPQIRFLTPIYHPNIDSAGRICLDVLKLPPKGAWRPSLN
IATVLTSIQLLMSEPNPDDPLMADISSEFKYNKPAFLKNARQWTEKHARQ
K
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5ojj Chain A Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ojj Mind the Metal: A Fragment Library-Derived Zinc Impurity Binds the E2 Ubiquitin-Conjugating Enzyme Ube2T and Induces Structural Rearrangements.
Resolution1.85 Å
Binding residue
(original residue number in PDB)		C86 K91
Binding residue
(residue number reindexed from 1)		C83 K88
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) C86
Catalytic site (residue number reindexed from 1) C83
Enzyme Commision number 2.3.2.23: E2 ubiquitin-conjugating enzyme.
External links
PDB RCSB:5ojj, PDBe:5ojj, PDBj:5ojj
PDBsum5ojj
PubMed28933844
UniProtQ9NPD8|UBE2T_HUMAN Ubiquitin-conjugating enzyme E2 T (Gene Name=UBE2T)

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