Structure of PDB 5oj4 Chain A Binding Site BS01

Receptor Information
>5oj4 Chain A (length=445) Species: 1122247 (Mycolicibacterium hassiacum DSM 44199) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHDPSFTPTQLAARAAYLLRGNDLGTMTTAAPLLYPHMWSWDAAFVAIGL
APLSVERAVVELDTLLSAQWRNGMIPHIVFANGVDGYFPGPARWATATLA
DNAPRNRLTSGITQPPVHAIAVQRILEHARTRGRSTRAVAEAFLDRRWGD
LMRWHRWLAECRDRNERGRITLYHGWESGMANSPRWDSAYANVVPGKLPE
YQRADNVIITDPSQRPSDGEYDRYLWLLEEMKAVRYDDERLPSVMSFQVE
DVFFSAIFSVACQVLAEIGEDYKRPHADVKDLYLWAERFRAGVVETTDQR
TGAARDFDVLAEKWLVTETAAQFAPLLCGGLPHDRERALLKLLEGPRFCG
HPDLKYGLIPSTSPVSRDFRPREYWRGPVWPVLTWLFSWCFARRGWAERA
RLLRQEGLRQASDGSFAEYYEPFTGEPLGSMQQSWTAAAVLDWLG
Ligand information
Ligand IDGLY
InChIInChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)
InChIKeyDHMQDGOQFOQNFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C(=O)O)N
CACTVS 3.341NCC(O)=O
ACDLabs 10.04O=C(O)CN
FormulaC2 H5 N O2
NameGLYCINE
ChEMBLCHEMBL773
DrugBankDB00145
ZINCZINC000004658552
PDB chain5oj4 Chain A Residue 513 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5oj4 The structural characterization of a glucosylglycerate hydrolase provides insights into the molecular mechanism of mycobacterial recovery from nitrogen starvation.
Resolution1.79 Å
Binding residue
(original residue number in PDB)		D86 G87 Y88
Binding residue
(residue number reindexed from 1)		D85 G86 Y87
Annotation score1
Enzymatic activity
Enzyme Commision number 3.2.1.208: glucosylglycerate hydrolase.
Gene Ontology
Molecular Function
GO:0004573 Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
GO:0016787 hydrolase activity
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0102547 glucosylglycerate hydrolase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006487 protein N-linked glycosylation
GO:0009311 oligosaccharide metabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:5oj4, PDBe:5oj4, PDBj:5oj4
PDBsum5oj4
PubMed31316802
UniProtK5BDL0|GGH_MYCHD Glucosylglycerate hydrolase (Gene Name=ggh)

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