Structure of PDB 5o9s Chain A Binding Site BS01

Receptor Information
>5o9s Chain A (length=378) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RSYQFWDTQPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLG
DRGVLKELYTLLNENYVEDDDNMFRFDYSPEFLLWALRPPGWLPQWHCGV
RVVSSRKLVGFISAIPANIHIYDTEKKMVEINFLCVHKKLRSKRVAPVLI
REITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLNPRKLIEVKFSHL
SNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHLTPV
MSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHKSLKA
AYSFYNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFG
IGDGNLQYYLYNWKCPSMGAEKVGLVLQ
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5o9s Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
V181 D183 F188 F190 T282 A283 Y296 H298 G468 I469 G470 D471 Q496
Binding residue
(residue number reindexed from 1)
V67 D69 F74 F76 T168 A169 Y182 H184 G350 I351 G352 D353 Q378
Enzymatic activity
Enzyme Commision number 2.3.1.-
2.3.1.97: glycylpeptide N-tetradecanoyltransferase.
Gene Ontology
Molecular Function
GO:0004379 glycylpeptide N-tetradecanoyltransferase activity
Biological Process
GO:0006499 N-terminal protein myristoylation

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Molecular Function

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Biological Process
External links
PDB RCSB:5o9s, PDBe:5o9s, PDBj:5o9s
PDBsum5o9s
PubMed29892081
UniProtP30419|NMT1_HUMAN Glycylpeptide N-tetradecanoyltransferase 1 (Gene Name=NMT1)

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