Structure of PDB 5o6b Chain A Binding Site BS01

Receptor Information
>5o6b Chain A (length=528) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GLSKEQESIIKLAENGHNIFYTGSAGTGKSILLREMIKVLKGIYGRENVA
VTASTGLAACNIGGITIHSFAGIGLGKGDADKLYKKVRRSRKHLRRWENI
GALVVDEISMLDAELLDKLDFIARKIRKNHQPFGGIQLIFCGDFFQLPPV
SKPTKFAFESKAWKEGVKMTIMLQKVFRQRGDVKFIDMLNRMRLGNIDDE
TEREFKKLSRPLPDDEIIPAELYSTRMEVERANNSRLSKLPGQVHIFNAI
DGGALEDEELKERLLQNFLAPKELHLKVGAQVMMVKNLDATLVNGSLGKV
IEFMDPETYFCYEALTNDPSMPPEKLETWAENPSKLKAAMEREQSAVASR
KSSVKEGFAKSDIGEPVSPLDSSVFDFMKRVVLENIKRKEQLMQTIHQNS
AGKRRLPLVRFKASDMSTRMVLVEPEDWAIEDENEKPLVSRVQLPLMLAW
SLSIHKSQGQTLPKVKVDLRRVFEKGQAYVALSRAVSREGLQVLNFDRTR
IKAHQKVIDFYLTLSSAESAYKQLEADE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5o6b Insights into the structural and mechanistic basis of multifunctional S. cerevisiae Pif1p helicase.
Resolution2.029 Å
Binding residue
(original residue number in PDB)		T290 G291 T301 H303 S304 G309 L310 V385 K387 T464 R465 N526 N533 S703 H705 K706 F723
Binding residue
(residue number reindexed from 1)		T55 G56 T66 H68 S69 G74 L75 V150 K152 T225 R226 N287 N294 S453 H455 K456 F473
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
Gene Ontology
Molecular Function
GO:0003678 DNA helicase activity
Biological Process
GO:0000723 telomere maintenance
GO:0006281 DNA repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5o6b, PDBe:5o6b, PDBj:5o6b
PDBsum5o6b
PubMed29202194
UniProtP07271|PIF1_YEAST ATP-dependent DNA helicase PIF1 (Gene Name=PIF1)

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