Structure of PDB 5nyy Chain A Binding Site BS01

Receptor Information
>5nyy Chain A (length=281) Species: 471852 (Thermomonospora curvata DSM 43183) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLYFQGHMVAIPGGTFRMGGEDPDAFPEDGEGPVRTVRLSPFLIDRYAVS
NRQFAAFVKATGYVTDAERYGWSFVFHAHVVVPEAPWWVAVPGAYWKAPE
GPGSSITDRPNHPVVHVSWNDAVAYATWAGKRLPTEAEWEMAARGGLDQA
RYPWGNELTPRGRHRCNIWQGTFPVHDTGEDGYTGTAPVNAFAPNGYGLY
NVAGNVWEWCADWWSADWHATESPATRIDPRGPETGTARVTKGGSFLCHE
SYCNRYRVAARTCNTPDSSAAHTGFRCAADP
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5nyy Chain A Residue 406 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5nyy Structural Basis for Copper-Oxygen Mediated C-H Bond Activation by the Formylglycine-Generating Enzyme.
Resolution1.28 Å
Binding residue
(original residue number in PDB)		N188 I189 D202 Y204
Binding residue
(residue number reindexed from 1)		N167 I168 D181 Y183
Annotation score1
Enzymatic activity
Enzyme Commision number 1.8.3.7: formylglycine-generating enzyme.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0120147 formylglycine-generating oxidase activity
GO:1903136 cuprous ion binding
Biological Process
GO:0018158 protein oxidation
GO:0043687 post-translational protein modification

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Molecular Function
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Biological Process
External links
PDB RCSB:5nyy, PDBe:5nyy, PDBj:5nyy
PDBsum5nyy
PubMed28544744
UniProtD1A7C3|FGE_THECD Formylglycine-generating enzyme (Gene Name=Tcur_4811)

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