Structure of PDB 5nng Chain A Binding Site BS01

Receptor Information
>5nng Chain A (length=127) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPTEE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5nng Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution1.2 Å
Binding residue
(original residue number in PDB)
W81 L92 L94 N140
Binding residue
(residue number reindexed from 1)
W40 L51 L53 N99
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5nng, PDBe:5nng, PDBj:5nng
PDBsum5nng
PubMed30554943
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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