Structure of PDB 5nnf Chain A Binding Site BS01
Receptor Information
>5nnf Chain A (length=126) Species:
9606
(Homo sapiens) [
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MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPTEE
Ligand information
>5nnf Chain B (length=8) Species:
9606
(Homo sapiens) [
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FLPHKYDV
Receptor-Ligand Complex Structure
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PDB
5nnf
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution
1.15 Å
Binding residue
(original residue number in PDB)
W81 V87 L92 L94 Y139 N140 K141 P142 G143 D144 D145 I146
Binding residue
(residue number reindexed from 1)
W39 V45 L50 L52 Y97 N98 K99 P100 G101 D102 D103 I104
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nnf
,
PDBe:5nnf
,
PDBj:5nnf
PDBsum
5nnf
PubMed
30554943
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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