Structure of PDB 5nne Chain A Binding Site BS01
Receptor Information
>5nne Chain A (length=125) Species:
9606
(Homo sapiens) [
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SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
Ligand information
>5nne Chain C (length=10) Species:
9606
(Homo sapiens) [
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GKAKGKKTQM
Receptor-Ligand Complex Structure
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PDB
5nne
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution
1.15 Å
Binding residue
(original residue number in PDB)
W81 V87 N93 Y139 D145 M149
Binding residue
(residue number reindexed from 1)
W40 V46 N52 Y98 D104 M108
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nne
,
PDBe:5nne
,
PDBj:5nne
PDBsum
5nne
PubMed
30554943
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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