Structure of PDB 5nnc Chain A Binding Site BS01
Receptor Information
>5nnc Chain A (length=125) Species:
9606
(Homo sapiens) [
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SMNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVK
LNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNK
PGDDIVLMAEALEKLFLQKINELPT
Ligand information
>5nnc Chain C (length=8) Species:
9606
(Homo sapiens) [
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KSTGGKAP
Receptor-Ligand Complex Structure
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PDB
5nnc
Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.
Resolution
2.22 Å
Binding residue
(original residue number in PDB)
W81 P82 V87 N140 D144 I146
Binding residue
(residue number reindexed from 1)
W40 P41 V46 N99 D103 I105
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nnc
,
PDBe:5nnc
,
PDBj:5nnc
PDBsum
5nnc
PubMed
30554943
UniProt
O60885
|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)
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