Structure of PDB 5njk Chain A Binding Site BS01
Receptor Information
>5njk Chain A (length=147) Species:
9606
(Homo sapiens) [
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WQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKG
FFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFD
RAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQK
Ligand information
>5njk Chain G (length=7) Species:
9606
(Homo sapiens) [
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AYIGPYL
Receptor-Ligand Complex Structure
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PDB
5njk
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
Resolution
3.13 Å
Binding residue
(original residue number in PDB)
R53 I111 V114 S115 F116 C117 R132 S155 G159 F162
Binding residue
(residue number reindexed from 1)
R29 I87 V90 S91 F92 C93 R108 S131 G135 F138
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5njk
,
PDBe:5njk
,
PDBj:5njk
PDBsum
5njk
PubMed
29269425
UniProt
P49757
|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)
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