Structure of PDB 5nig Chain A Binding Site BS01

Receptor Information
>5nig Chain A (length=180) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEFD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5nig Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint.
Resolution1.35 Å
Binding residue
(original residue number in PDB)		Q9 E11 F24 A52 S53 F54 G58 N62 V65 D66 N69 I72 K75
Binding residue
(residue number reindexed from 1)		Q8 E10 F23 A51 S52 F53 G57 N61 V64 D65 N68 I71 K74
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:5nig, PDBe:5nig, PDBj:5nig
PDBsum5nig
PubMed29853344
UniProtP01903|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)

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