Structure of PDB 5ni9 Chain A Binding Site BS01
Receptor Information
>5ni9 Chain A (length=179) Species:
9606
(Homo sapiens) [
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KEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETVWRLEEFGRF
ASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELRE
PNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL
PFLPSTEDVYDCRVEHWGLDEPLLKHWEF
Ligand information
>5ni9 Chain C (length=14) Species:
9606
(Homo sapiens) [
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KRIAKAVNEKSCNC
Receptor-Ligand Complex Structure
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PDB
5ni9
Memory T cells specific to citrullinated alpha-enolase are enriched in the rheumatic joint.
Resolution
1.33 Å
Binding residue
(original residue number in PDB)
Q9 E11 F24 F51 A52 S53 F54 G58 N62 V65 D66 N69 I72 K75 R76
Binding residue
(residue number reindexed from 1)
Q8 E10 F23 F50 A51 S52 F53 G57 N61 V64 D65 N68 I71 K74 R75
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Biological Process
GO:0006955
immune response
GO:0019882
antigen processing and presentation
Cellular Component
GO:0016020
membrane
GO:0042613
MHC class II protein complex
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Biological Process
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Cellular Component
External links
PDB
RCSB:5ni9
,
PDBe:5ni9
,
PDBj:5ni9
PDBsum
5ni9
PubMed
29853344
UniProt
P01903
|DRA_HUMAN HLA class II histocompatibility antigen, DR alpha chain (Gene Name=HLA-DRA)
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