Structure of PDB 5nft Chain A Binding Site BS01
Receptor Information
>5nft Chain A (length=248) Species:
9606
(Homo sapiens) [
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TPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQMIAAVKWA
KAIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLI
INEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKD
GLKSQALFDEIRMTYIKELGKAIVKREGNSSQNSQRFYQLTKLLDSMHEV
VENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>5nft Chain B (length=13) Species:
9606
(Homo sapiens) [
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ENALLRYLLDKDD
Receptor-Ligand Complex Structure
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PDB
5nft
Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
V575 K579 R585 L589 M593 Q597 E751 M752 E755 N759
Binding residue
(residue number reindexed from 1)
V47 K51 R57 L61 M65 Q69 E223 M224 E227 N231
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nft
,
PDBe:5nft
,
PDBj:5nft
PDBsum
5nft
PubMed
28937774
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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