Structure of PDB 5nfp Chain A Binding Site BS01
Receptor Information
>5nfp Chain A (length=247) Species:
9606
(Homo sapiens) [
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PTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQMIAAVKWAK
AIPGFRNLHLDDQMTLLQYSWMSLMAFALGWRSYRQSSANLLCFAPDLII
NEQRMTLPDMYDQCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSSVPKDG
LKSQELFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEVV
ENLLNYCFQTFLDKTMSIEFPEMLAEIITNQIPKYSNGNIKKLLFHQ
Ligand information
>5nfp Chain B (length=13) Species:
9606
(Homo sapiens) [
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ENALLRYLLDKDD
Receptor-Ligand Complex Structure
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PDB
5nfp
Selective Nonsteroidal Glucocorticoid Receptor Modulators for the Inhaled Treatment of Pulmonary Diseases.
Resolution
2.1 Å
Binding residue
(original residue number in PDB)
V575 K579 R585 L589 M593 Q597 E751 M752 E755 N759
Binding residue
(residue number reindexed from 1)
V46 K50 R56 L60 M64 Q68 E222 M223 E226 N230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nfp
,
PDBe:5nfp
,
PDBj:5nfp
PDBsum
5nfp
PubMed
28937774
UniProt
P04150
|GCR_HUMAN Glucocorticoid receptor (Gene Name=NR3C1)
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