Structure of PDB 5naf Chain A Binding Site BS01

Receptor Information
>5naf Chain A (length=352) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VEIPSNKAVVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSGP
TQLVLRHCIREGSNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLAST
LGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPA
LDVDWQSNNTFASCSTDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTG
NLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPNA
NLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGS
FDKCVHIWNTQTGALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLD
LR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5naf Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.
Resolution2.493 Å
Binding residue
(original residue number in PDB)		E171 F270 L312 N353 D369 Y395 Y446 F462 F487
Binding residue
(residue number reindexed from 1)		E17 F109 L151 N192 D208 Y234 Y285 F301 F326
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003714 transcription corepressor activity

View graph for
Molecular Function
External links
PDB RCSB:5naf, PDBe:5naf, PDBj:5naf
PDBsum5naf
PubMed28348241
UniProtQ8BHJ5|TBL1R_MOUSE F-box-like/WD repeat-containing protein TBL1XR1 (Gene Name=Tbl1xr1)

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