Structure of PDB 5n9f Chain A Binding Site BS01 |
| >5n9f Chain A (length=859) Species: 7227 (Drosophila melanogaster)
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IRLGCNVSAPSGVLERVKELMEDYSRAPDAKFQQQFRHLLSVNFEEFVAE
TKERNADLDWVNPKLDERLQLELGQRQLEENAKKRLEARKKLPTMKYADD
IIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPR
RISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQ
QLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSA
TVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKPPERRM
KHEAMIEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENE
PEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRDHMAVFPLHSLMQSGE
QQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETN
IQSLDEVWVTKANTQQRRGRAGRVRPGICYNLFSRAREDRMDDIPTPEIL
RSKLESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLKRIEALDQ
TGTLTPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFKSPFY
SPLGKESRVDEIKRRMARNMRSDHLMVHNTIIAYRDSRYSHAERDFCYKN
FLSSMTLQQLERMKNQFSELLYNYKFLASSNCKDAASNKNSEKIPLLRAI
IGAGLYPNMAHLRKSRQIKNRVRAIHTMATDDGRRVNFHPSSVNSGESGF
DSAYFVYFQRQKSTDLFLLDSTMVFPMALIIFGDGVEAGVTQNTPYLCVA
KTYYFKCNRETADVVIQLRSNLEKLLLKKALYPAPIEENGYEKQLIKAIE
LLLSLDERL |
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| PDB | 5n9f Structural and mechanistic insights into DHX36-mediated innate immunity and G-quadruplex unfolding |
| Resolution | 2.969 Å |
Binding residue
(original residue number in PDB) | R211 R212 R239 T255 G257 V258 Q261 Q262 S265 G431 Y432 H463 S464 L465 T489 I490 I491 T494 S495 K511 T513 L524 P635 I636 D637 S664 D680 R793 H809 P810 S811 S833 |
Binding residue
(residue number reindexed from 1) | R150 R151 R178 T194 G196 V197 Q200 Q201 S204 G361 Y362 H393 S394 L395 T419 I420 I421 T424 S425 K441 T443 L454 P565 I566 D567 S594 D610 R723 H739 P740 S741 S763 |
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| Enzyme Commision number |
3.6.4.13: RNA helicase. |
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