Structure of PDB 5n9c Chain A Binding Site BS01
Receptor Information
>5n9c Chain A (length=113) Species:
9606
(Homo sapiens) [
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GSMSEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRV
VGRKIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDAN
VFASAMMHALEVL
Ligand information
>5n9c Chain F (length=3) Species:
32630
(synthetic construct) [
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PPt
Receptor-Ligand Complex Structure
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PDB
5n9c
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
1.16 Å
Binding residue
(original residue number in PDB)
Y16 W23 K69 N71 F77 Q79 R81 V86
Binding residue
(residue number reindexed from 1)
Y18 W25 K71 N73 F79 Q81 R83 V88
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5n9c
,
PDBe:5n9c
,
PDBj:5n9c
PDBsum
5n9c
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
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