Structure of PDB 5n96 Chain A Binding Site BS01 |
| >5n96 Chain A (length=849) Species: 7227 (Drosophila melanogaster)
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IRLGCNVSAPSGVLERVKELMEDYSRAPDAKFQQQFRHLLSVNFEEFVAE
TKERNADLDWVNPKLDERLQLELGQRQLEENAKKRLEARKKLPTMKYADD
IIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPR
RISAIAIAEWVSYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQ
QLQSDPLMHNLSVLILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSA
TVREQDFCDYFNNCPMFRIEGVMFPVKMLYLEDVLSKTNYEFQKRMKHEA
MIEPYLRRIRNSYDSRVLDKLRLPESEGCEDIDFIADLVYYICENEPEGA
ILVFLPGYDKISQLYNILDKPKTSKGQRWRDHMAVFPLHSLMQSGEQQAV
FRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNYDIETNIQSL
DEVWVTKANTQQRRGRAGRVRPGICYNLFSRAREDRMDDIPTPEILRSKL
ESIILSLKLLHIDDPYRFLQTLINAPNPEAIKMGVELLKRIEALDQTGTL
TPLGMHLAKLPIDPQMGKMILMSALFCCLDPITSAAAALSFKSPFYSPLG
KESRVDEIKRRMARNMRSDHLMVHNTIIAYRDSRYSHAERDFCYKNFLSS
MTLQQLERMKNQFSELLYNYKFLASSNCKDAASNKNSEKIPLLRAIIGAG
LYPNMAHLRKSRRAIHTMATDDGRRVNFHPSSVNSGESGFDSAYFVYFQR
QKSTDLFLLDSTMVFPMALIIFGDGVEAGVTQNTPYLCVAKTYYFKCNRE
TADVVIQLRSNLEKLLLKKALYPAPIEENGYEKQLIKAIELLLSLDERL |
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| PDB | 5n96 Molecular Mechanistic Insights into Drosophila DHX36-Mediated G-Quadruplex Unfolding: A Structure-Based Model. |
| Resolution | 2.716 Å |
Binding residue
(original residue number in PDB) | R211 R212 Q237 I238 R239 T255 G257 V258 Q261 Q264 S265 G431 Y432 H463 S464 L465 T489 I491 S495 K511 T513 L524 P635 F665 D680 Q736 R793 H809 P810 S811 S833 T834 F837 |
Binding residue
(residue number reindexed from 1) | R150 R151 Q176 I177 R178 T194 G196 V197 Q200 Q203 S204 G357 Y358 H389 S390 L391 T415 I417 S421 K437 T439 L450 P561 F591 D606 Q662 R713 H729 P730 S731 S753 T754 F757 |
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| Enzyme Commision number |
3.6.4.13: RNA helicase. |
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