Structure of PDB 5n8m Chain A Binding Site BS01

Receptor Information
>5n8m Chain A (length=155) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GGSLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQPNF
TFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGCNPVGALQELVVQKG
WRLPEYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKML
LRVHT
Ligand information
>5n8m Chain B (length=21) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uuaauuaucuauuccguacuu
.....................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5n8m Structural basis of siRNA recognition by TRBP double-stranded RNA binding domains.
ResolutionN/A
Binding residue
(original residue number in PDB)		E37 T40 A57 P60 F62 S79 K80 N159 V161 L175 A187 H188 K211 K214 R215
Binding residue
(residue number reindexed from 1)		E25 T28 A45 P48 F50 S67 K68 N87 V89 L103 A115 H116 K139 K142 R143
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5n8m, PDBe:5n8m, PDBj:5n8m
PDBsum5n8m
PubMed29449323
UniProtQ15633|TRBP2_HUMAN RISC-loading complex subunit TARBP2 (Gene Name=TARBP2)

[Back to BioLiP]