Structure of PDB 5n7q Chain A Binding Site BS01

Receptor Information
>5n7q Chain A (length=337) Species: 34613 (Ixodes ricinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCTTK
YCLHHHRYDSSKSSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKVSG
QPLGEALVVGGESLLEAPFDGILGLAYPSIAVDGVVPVFDNMMKQGLLGE
QNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKGSITYVPVTAKGYWQFHVD
GVKSVSASKSAPELLCKDGCEAIADTGTSLITGPPEEVDSLNQYLGGTKT
EGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVSGF
MGLEMPQPLWILGDVFLGPYYTIFDRDQDRVGFAEVA
Ligand information
Receptor-Ligand Complex Structure
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PDB5n7q Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Resolution1.45 Å
Binding residue
(original residue number in PDB)		D36 G38 V78 Y79 G80 S81 Y196 D227 G229 T230 S231 Q256 M307
Binding residue
(residue number reindexed from 1)		D34 G36 V76 Y77 G78 S79 Y194 D225 G227 T228 S229 Q254 M305
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5n7q, PDBe:5n7q, PDBj:5n7q
PDBsum5n7q
PubMed29396291
UniProtV5HCK7

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