Structure of PDB 5n70 Chain A Binding Site BS01

Receptor Information
>5n70 Chain A (length=339) Species: 34613 (Ixodes ricinus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IHEGPYPEPLVNLLDVVYYGPISIGTPPQDFQVIFDTGSANLWLPSSKCT
TKYCLHHHRYDSSKSSTYEADGRNFTIVYGSGNVEGFISKDVCRIGSAKV
SGQPLGEALVVGGESLLEAPFDGILGLAYPSIAVDGVVPVFDNMMKQGLL
GEQNVFSVYLNRDPSSKEGGEVLFGGIDHDHYKGSITYVPVTAKGYWQFH
VDGVKSVSASKSAPELLCKDGCEAIANTGTSLITGPPEEVDSLNQYLGGT
KTEGGQYLLDCDKLESLPNVTFTISGKEFSLRSKDYVLKVNQQGQTLCVS
GFMGLEMPQPLWILGDVFLGPYYTIFDRDQDRVGFAEVA
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5n70 Novel Structural Mechanism of Allosteric Regulation of Aspartic Peptidases via an Evolutionarily Conserved Exosite.
Resolution1.81 Å
Binding residue
(original residue number in PDB)		Y40 Y41 I117 G118 A120 M166 R184 G191 G192 E193 V194 L195 F196 G197
Binding residue
(residue number reindexed from 1)		Y18 Y19 I95 G96 A98 M144 R162 G169 G170 E171 V172 L173 F174 G175
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5n70, PDBe:5n70, PDBj:5n70
PDBsum5n70
PubMed29396291
UniProtV5HCK7

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