Structure of PDB 5n6x Chain A Binding Site BS01

Receptor Information
>5n6x Chain A (length=396) Species: 446 (Legionella pneumophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PGSISLGDLHGNAIKLIHFLFRHKIIKFKTEIINFHEAYQQFVTIYEQYD
DMVQEYLEIRTLLQLIQIKITNAQQRILDIEQKLSLATDHQKEFSQSLLQ
LKKPIEANLQMAEKSKAGLEEKLSGLKTRLPSCIERFNKFMTQIEINDIK
TLIRLLGDEVADRGSCDYFTLRILDFLYQNQIAIKIILSNHGYEFIHAYE
KLVVGQPFKPKGYIGDIQIKSFWGLQLLLEQSVITEEELRSLVERAYKPT
LKIIDYSLSEDGITLYSHAPIRFDSIRMAASQLGVTYNDSTKEALAETID
QLNAQLQIYMKNNMLHLLFENNEINDPTNMTDEERNASPLIYLVWNRWNE
SKEVENARPGKYNGYFVTYVHGHDPFQSPLTYVYNLDTLCGKYSRV
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5n6x Chain A Residue 501 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5n6x Structure of the WipA protein reveals a novel tyrosine protein phosphatase effector from Legionella pneumophila.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		D180 N212 H290
Binding residue
(residue number reindexed from 1)		D158 N190 H268
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016791 phosphatase activity

View graph for
Molecular Function
External links
PDB RCSB:5n6x, PDBe:5n6x, PDBj:5n6x
PDBsum5n6x
PubMed28389563
UniProtQ5GA16

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