Structure of PDB 5n2j Chain A Binding Site BS01

Receptor Information
>5n2j Chain A (length=1373) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ASPSINVALKAAFPSPPYLVELLETAASDNTTIYYSLLDRIAKGHFAEAT
TDKALYEKFLEVLRDDGHMDPEALSAFKLALSLRTATPRVEAHYQYYTAT
VEPSLSGTQEGCDQWFLIDGEQYCSPTLDTSHGKVKGEDQLRTLPFDRKF
GVGSRDVILYADITSKSFAPFHEVAMDLAKKGKASYRVRYRRSPSHSRES
LSVNGYGVELVLKRTDYIVKSELAALGMKAASFVMQSEKPFEALLKLTQD
FPKYSNSLGSQNVSAEFEAEHRGNREVFLPEGSNVLWLNGLHLIDRQIQP
FGLVDLLTRERKLIKSVLDLGLTGQQAVDLLGHAEVAHAKSGDDEPRRFD
WRDDIEEGQVIIWLNNLEKDKRYKSFSPSIWVLIHHFGHGLPQIRRDVFN
LVVPVDLTKADDVKIVVEGLLSFVKRLIPVRFGFVPLTPTGQAIDQAKVV
YYLLENYGLAAATAYLEKSYEEQSTGQPNERIFNEVIKDKSLRPDGVELS
FKDIFISEKHEKQIHLSKHWVERLRAGGDVPTVFFDGFPIPREDNWLRVM
NHRLMQDLQALQQAGYFGMLNESMWLPGFFLEKALSRRNTLIFPEDKNEL
TVLNVNKIYIENHDLMSKVPVIEASKESTRDDWAALTVVADLDDIEGQEL
VYYALRFRKSNDGVRLDIVHNPKDTSRSPSVLAQRLKSREDKLLDFTRFL
DLETALETGEFEPDVAYDASLANFLASSNMKAGDNFVILNGRVLGPITSA
DDFKKEDFEVFLQAERRTRILPVYKALEDLGLDDKVSGPLSAAKLTSVTA
LSTISDLPQGIFDNAPTVRTTLFKQWNSTYTSFEVGDASTATIFFVAVIN
PASEIGQRWVAVLKVLSELEGVHLRVFLNPTVMIEELPVKRFYRYVLSSS
PSFDESGKVKALSARFTGVPRETLLVVGMDVPPAWLVTSKVAVDDLDNLR
IKDIKAKRGTEHVEAIYELEHILIEGHSREIPGAHAPRGVQLVLETENNP
HFADTIIMANLGYFQFKANPGVYNIRLKEGRSSEIFTLESVGAKGWGPIP
GDDNTEVVLMDFQGTTLYPRLRRKPGMEEEDVLEPEATKSVSKTEHAEIN
IFSVASGHLYERMLNIMMASVMHHTNHTVKFWFIEQFLSPSFKDFIPHMA
AEYGFKYEMVTYKWPHWLRQQKEKQREIWGYKILFLDVLFPLSLDKVIFV
DADQIVRTDMYDLVEHPLDGAPYGFAPMCDSRVEMEGYRFWKTGYWANYL
KGKPYHISALYVVDLQRFRELAAGDRLRQQYHALSADPNSLANLDQDLPN
HMQFTIPIATLPQEWLWCETWCSDETLKDARTIDLCNNPMTKEPKLDRAR
RQVPEWTKYDEEIAELARRVREE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5n2j Chain A Residue 1613 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5n2j Interdomain conformational flexibility underpins the activity of UGGT, the eukaryotic glycoprotein secretion checkpoint.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		D1302 D1304 D1435
Binding residue
(residue number reindexed from 1)		D1201 D1203 D1334
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity
Biological Process
GO:0006486 protein glycosylation

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5n2j, PDBe:5n2j, PDBj:5n2j
PDBsum5n2j
PubMed28739903
UniProtG0SB58

[Back to BioLiP]