Structure of PDB 5n1y Chain A Binding Site BS01

Receptor Information
>5n1y Chain A (length=277) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRA
PWIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMY
GCDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEA
AHVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEA
TLRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVV
PSGQEQRYTCHVQHEGLPKPLTLRWEP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5n1y Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity.
Resolution1.39 Å
Binding residue
(original residue number in PDB)
Y7 E63 K66 H70 T73 D77 Y84 Y99 T143 W147 L156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y8 E64 K67 H71 T74 D78 Y85 Y100 T144 W148 L157 Y160 W168 Y172
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5n1y, PDBe:5n1y, PDBj:5n1y
PDBsum5n1y
PubMed27183389
UniProtP04439|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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