Structure of PDB 5mza Chain A Binding Site BS01

Receptor Information
>5mza Chain A (length=440) Species: 36329 (Plasmodium falciparum 3D7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNPCAKPHGKKLATVKQIAQYYKRKAYIQLNERGSRSALKGDASQGQYDR
GGKADDFKTKLCEINEKHSNARSNSLNPCNGKDNNKVRFNVGTPWQSGEK
IATATDVYLPPRRQHFCTSNLEYLINGGHQAILNVKNGKINHSFLGDVLL
AAKYQAQHTMKDYKSKNDKEGICRAIRYSFADIGDIIKGTDLWDKDGGEI
KTQNHLVTIFDKIKAQLPKDIKGKYTGTKHLELRKDWWEANRDQVWKAMQ
CGNDNPCSGESDHTPLHDYIPQRLRWMTEWAEWYCKEQSRLYDKLKVCEE
SGECATCKEACEEYNKEIKKWEQQWDAISYKYLMLYAKARITAINGGPGY
YNTEVQEEDKPVVDFLYNLYLQNGGKKGPPPDTHRVKATPYSTAAGYIHQ
EAHIGDCQKQTQFCKNKNGEADPTYAFRDKPHDHDTACKC
Ligand information
Ligand ID3PO
InChIInChI=1S/H5O10P3/c1-11(2,3)9-13(7,8)10-12(4,5)6/h(H,7,8)(H2,1,2,3)(H2,4,5,6)
InChIKeyUNXRWKVEANCORM-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341O[P](O)(=O)O[P](O)(=O)O[P](O)(O)=O
OpenEye OEToolkits 1.5.0OP(=O)(O)OP(=O)(O)OP(=O)(O)O
ACDLabs 10.04O=P(OP(=O)(O)OP(=O)(O)O)(O)O
FormulaH5 O10 P3
NameTRIPHOSPHATE
ChEMBLCHEMBL1230191
DrugBankDB03896
ZINCZINC000006827739
PDB chain5mza Chain A Residue 1301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5mza Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria.
Resolution2.78 Å
Binding residue
(original residue number in PDB)		Y880 Q883 H884 K887
Binding residue
(residue number reindexed from 1)		Y154 Q157 H158 K161
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:5mza, PDBe:5mza, PDBj:5mza
PDBsum5mza
PubMed28279348
UniProtQ8IHM0

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