Structure of PDB 5mr8 Chain A Binding Site BS01
Receptor Information
>5mr8 Chain A (length=186) Species:
9606
(Homo sapiens) [
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PNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDI
GKPEVEYDCDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQE
PVPASIPNYYKIIKKPMDLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKN
CERFNEADSEVAQAGKAVALYFEDKLTEIYSDRTFA
Ligand information
>5mr8 Chain C (length=9) Species:
9606
(Homo sapiens) [
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ARTKQTARK
Receptor-Ligand Complex Structure
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PDB
5mr8
Crystal structure of TRIM33 PHD-Bromodomain isoform B in complex with H3K9ac histone peptide
Resolution
1.74 Å
Binding residue
(original residue number in PDB)
N886 E887 N895 G896 G897 D898 L899 C901 E903 H910 P922 G924
Binding residue
(residue number reindexed from 1)
N2 E3 N11 G12 G13 D14 L15 C17 E19 H26 P38 G40
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:5mr8
,
PDBe:5mr8
,
PDBj:5mr8
PDBsum
5mr8
PubMed
UniProt
Q9UPN9
|TRI33_HUMAN E3 ubiquitin-protein ligase TRIM33 (Gene Name=TRIM33)
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