Structure of PDB 5mkw Chain A Binding Site BS01

Receptor Information
>5mkw Chain A (length=119) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMSNNSYLRAKVFETEHGVCQLCNVNAQELFLRLRDAPKSQRKNLLYATW
TSKLPLEQLNEMIRNPGEGHFWQVDHIKPVYGGGGQCSLDNLQTLCTVCH
KERTARQAKERSQVRRQSL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5mkw Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5mkw Structural insights into the function of ZRANB3 in replication stress response.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		C20 C23 C96 C99
Binding residue
(residue number reindexed from 1)		C20 C23 C96 C99
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.-.-
3.6.4.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004519 endonuclease activity
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5mkw, PDBe:5mkw, PDBj:5mkw
PDBsum5mkw
PubMed28621305
UniProtQ5FWF4|ZRAB3_HUMAN DNA annealing helicase and endonuclease ZRANB3 (Gene Name=ZRANB3)

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