Structure of PDB 5mga Chain A Binding Site BS01 |
| >5mga Chain A (length=1182) Species: 401614 (Francisella tularensis subsp. novicida U112)
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IYQEFVNKYSLSKTLRFELIPQGKTLENIKARGLILDDEKRAKDYKKAKQ
IIDKYHQFFIEEILSSVCISEDLLQNYSDVYFKLKKSDDDNLQKDFKSAK
DTIKKQISEYIKDSEKFKNLFNQNLIDAKKGQESDLILWLKQSKDNGIEL
FKANSDITDIDEALEIIKSFKGWTTYFKGFHENRKNVYSSNDIPTSIIYR
IVDDNLPKFLENKAKYESLKDKAPYEQIKKDLAEELTFDDDYKNQRVFSL
DEVFEIANFNNYLNQSGITKFNTIIGGKFVNGENTKRKGINEYINLYSQN
DKTLKKYKMSVLFKQILSDTESKSFVIDKLEDDSDVVTTMQSFYEQIAAF
KTKETLSLLFDDLKKSLTDLSQQVFDDYKEQELIAKKTEKAKYLSLETIL
IDKQCRFEEILANFAAIPMIFDEIAQNKDNLAQISIKYQNQGKKDLLQAS
AEDDVKAIKDLLDQTNNLLHKLKIFHISQSEDKADEHFYLVFEECYFELA
NIVPLYNKIRNYITQKPYSDEKFKLNFENSTLANGWDKNKEPDNTAILFI
KDDKYYLGVMNKKNNKIFDDKAIKENKGEGYKKIVYKLLPGANKMLPKVF
FSAKSIKFYNPSEDILRIRNHSTHTKNGSPQKGYEKFEFNIEDCRKFIDF
YKQSISKHPEWKDFGFRFSDTQRYNSIDEFYREVENQGYKLTFENISESY
IDSVVNQGKLYLFQIYNKDFSAYSKGRPNLHTLYWKALFDERNLQDVVYK
LNGEAELFYRKQSIPKKIIANKNKDNPKKESVFEYDLIKDKRFTEDKFFF
HCPITINFKSSGANKFNDEINLLLKEKANDVHILSIDRGERHLAYYTLVD
GKGNIIKQDTFNIIGNYHDKLAAIEKDRDSARKDWKKINNIKEMKEGYLS
QVVHEIAKLVIEYNAIVVFEDLNFGVEKQVYQKLEKMLIEKLNYLVFKDN
EFDKTGGVLRAYQLTAPFETFKKMGKQTGIIYYVPAGFTSKICPVTGFVN
QLYPVSKSQEFFSKFDKICYNLDKGYFEFSFDYKNFGDKGKWTIASFGSR
LINNHNWDTREVYPTKELEKLLKDYGECIKAICGESDKKFFAKLTSVLNT
ILQMRNSKELDYLISPVADVNGNFFDSRQAPKNMPQDADANGAYHIGLKG
LMLLGRIKNNQEKLNLVIKNEEYFEFVQNRNN |
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| PDB | 5mga Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage. |
| Resolution | 3.0 Å |
Binding residue
(original residue number in PDB) | S14 K15 T16 R18 F19 K51 N185 R186 R202 T295 K296 L306 Q309 F325 K326 I328 L329 K397 V576 Y579 N580 R583 N790 K791 S794 Y796 S797 K798 G799 R800 N802 L803 H804 E829 F831 R833 I842 N851 K852 N853 K859 E860 Y865 I868 K869 K871 R872 F879 H881 Y953 K956 R968 K969 E979 M980 G983 S986 H990 V1019 K1034 K1041 |
Binding residue
(residue number reindexed from 1) | S12 K13 T14 R16 F17 K49 N183 R184 R200 T285 K286 L296 Q299 F313 K314 I316 L317 K365 V503 Y506 N507 R510 N717 K718 S721 Y723 S724 K725 G726 R727 N729 L730 H731 E756 F758 R760 I769 N771 K772 N773 K779 E780 Y785 I788 K789 K791 R792 F799 H801 Y867 K870 R882 K883 E893 M894 G897 S900 H904 V926 K941 K948 |
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| Enzyme Commision number |
3.1.21.1: deoxyribonuclease I.
4.6.1.22: Bacillus subtilis ribonuclease. |
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