Structure of PDB 5m3h Chain A Binding Site BS01

Receptor Information
>5m3h Chain A (length=699) Species: 11320 (Influenza A virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MENFVRTNFNPMILERAEKTMKEYGENPQNEGNKFAAISTHMEVCFMYSD
FHFIDLEGNTIVKENDDDNAMLKHRFEIIEGQERNIAWTIVNSICNMTEN
SKPRFLPDLYDYKTNKFIEIGVTRRKVEDYYYEKASKLKGENVYIHIFSF
DGEEMATDDEYILDEESRARIKTRLFVLRQELATALEEEFSYPPTFQRLA
NQSLPPSFKDYHQFKAYVSSFKANGNIEAKLGAMSEKVNAQIESFDPRTI
RELELPEGKFCTQRSKFLLMDAMKLSVLNPAHEGEGIPMKDAKACLDTFW
GWKKATIIKKHEKGVNTNYLMIWEQLLESIKEMEGKFLNLKKTNHLKWGL
GEGQAPEKMDFEDCKEVPDLFQYKSEPPEKRKLASWIQSEFNKASELTNS
NWIEFDELGNDVAPIEHIASRRRNFFTAEVSQCRASEYIMKAVYINTALL
NSSCTAMEEYQVIPIITKCRDTSGQRRTNLYGFIIKGRSHLRNDTDVVNF
ISLEFSLTDPRNEIHKWEKYCVLEIGDMEIRTSISTIMKPVYLYVRTNGT
SKIKMKWGMEMRRCLLQSLQQVESMIEAESAVKEKDMTEPFFRNRENDWP
IGESPQGIEKGTIGKVCRVLLAKSVFNSIYASAQLEGFSAESRKLLLLIQ
AFRDNLDPGTFDLKGLYEAIEECIINDPWVLLNASWFNSFLKAVQLSMG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5m3h Structural basis of an essential interaction between influenza polymerase and Pol II CTD.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		M472 H505 L506 R507 K567
Binding residue
(residue number reindexed from 1)		M457 H490 L491 R492 K552
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0046872 metal ion binding
Biological Process
GO:0039694 viral RNA genome replication
GO:0075523 viral translational frameshifting

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Molecular Function
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Biological Process
External links
PDB RCSB:5m3h, PDBe:5m3h, PDBj:5m3h
PDBsum5m3h
PubMed28002402
UniProtH6QM92

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