Structure of PDB 5lqv Chain A Binding Site BS01

Receptor Information

>5lqv Chain A (length=93) Species: 3864 (Lens culinaris)

AISCGAVTSDLSPCLTYLTGGPGPSPQCCGGVKKLLAAANTTPDRQAACN
CLKSAAGSITKLNTNNAAALPGKCGVNIPYKISTTTNCNTVKF

Ligand information

• Ligand ID: PGM
• InChI: InChI=1S/C22H45O9P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-22(26)29-17-21(25)19-31-32(27,28)30-18-20(24)16-23/h20-21,23-25H,2-19H2,1H3,(H,27,28)/p-1/t20-,21-/m0/s1
• InChIKey: BVJSKAUUFXBDOB-SFTDATJTSA-M
• SMILES:
  OpenEye OEToolkits 1.7.5: CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)([O-])OCC(CO)O)O
  CACTVS 3.385: CCCCCCCCCCCCCCCC(=O)OC[C@H](O)CO[P]([O-])(=O)OC[C@@H](O)CO
  OpenEye OEToolkits 1.7.5: CCCCCCCCCCCCCCCC(=O)OC[C@@H](COP(=O)([O-])OC[C@H](CO)O)O
  ACDLabs 10.04: O=C(OCC(O)COP([O-])(=O)OCC(O)CO)CCCCCCCCCCCCCCC
  CACTVS 3.385: CCCCCCCCCCCCCCCC(=O)OC[CH](O)CO[P]([O-])(=O)OC[CH](O)CO
• Formula: C22 H44 O9 P
• Name: 1-MYRISTOYL-2-HYDROXY-SN-GLYCERO-3-[PHOSPHO-RAC-(1-GLYCEROL)];
  LYSOPHOSPHATIDYLGLYCEROL
• DrugBank: DB03438
• PDB chain: 5lqv Chain A Residue 101

Receptor-Ligand Complex Structure

Structure summary

• PDB: 5lqv Ligand Binding Properties of the Lentil Lipid Transfer Protein: Molecular Insight into the Possible Mechanism of Lipid Uptake.
• Resolution: N/A
• Binding residue (original residue number in PDB): T8 L15 L35 L36 L52 K53 A55 A56 I59 L62 A67 I82
• Binding residue (residue number reindexed from 1): T8 L15 L35 L36 L52 K53 A55 A56 I59 L62 A67 I82
• Annotation score: 1

Gene Ontology

Molecular Function

• GO:0008289 lipid binding

Biological Process

• GO:0006869 lipid transport

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:5lqv, PDBe:5lqv, PDBj:5lqv
• PDBsum: 5lqv
• PubMed: 28266846
• UniProt: A0AT29|NLTP2_LENCU Non-specific lipid-transfer protein 2