Structure of PDB 5lmg Chain A Binding Site BS01

Receptor Information
>5lmg Chain A (length=316) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSS
YDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIIL
SSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIR
NNNVSFLTTSKIGLNLITILISRAALIKISTWNEIYDKLFTSLESKIQLI
FPPREYNDHIMRLQNDKFMDEAYIWAFLASLAASGKLNHQRIIIDEVRDE
IFATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFL
NVMGLVYRDGEISELK
Ligand information
>5lmg Chain D (length=13) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SGSNELLSILHRK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5lmg A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Resolution1.89 Å
Binding residue
(original residue number in PDB)		L717 Q720 R721 I724 D725 R728 M783 G784 L785 I792 E794
Binding residue
(residue number reindexed from 1)		L237 Q240 R241 I244 D245 R248 M303 G304 L305 I312 E314
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA

View graph for
Biological Process
External links
PDB RCSB:5lmg, PDBe:5lmg, PDBj:5lmg
PDBsum5lmg
PubMed29078363
UniProtP25644|PAT1_YEAST Deadenylation-dependent mRNA-decapping factor PAT1 (Gene Name=PAT1)

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