Structure of PDB 5lmf Chain A Binding Site BS01

Receptor Information
>5lmf Chain A (length=312) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSSYDVN
PFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIILSSYK
TTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIRNNNV
SFLTTSKIGLNLITILISRAALIKQSTWNEIYDKLFTSLESKIQLIFPPR
EYNDHIMRLQNDKFMDEAYIWAFLASLAASGKLNHQRIIIDEVRDEIFAT
INEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFLNVMG
LVYRDGEISELK
Ligand information
>5lmf Chain D (length=17) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
TAHSNSQALLDLLKKPT
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5lmf A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Resolution2.15 Å
Binding residue
(original residue number in PDB)		L717 Q720 R721 I724 R728 M783 L785 I792 E794
Binding residue
(residue number reindexed from 1)		L233 Q236 R237 I240 R244 M299 L301 I308 E310
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA

View graph for
Biological Process
External links
PDB RCSB:5lmf, PDBe:5lmf, PDBj:5lmf
PDBsum5lmf
PubMed29078363
UniProtP25644|PAT1_YEAST Deadenylation-dependent mRNA-decapping factor PAT1 (Gene Name=PAT1)

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