Structure of PDB 5lm8 Chain A Binding Site BS01

Receptor Information
>5lm8 Chain A (length=549) Species: 5061 (Aspergillus niger) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTPWQGYDINTNYYETIPQTNVVREYWFDIVNTTAALDGVERPVLLVNGQ
FPGPTIEANWGDTVKVHVTNRMENNGTAIHFHGIRQLYNNQMDGVAALTQ
CPVPPNSSYTYVWRAEEYGSSWYHSHFSLQAWEGVFGGILIHGPSTAEYD
HDLGMVFLNDWSHQTVDEMYQSVLESQNPPHFQTGLINGSNIWVTADNQT
VGRRFQTEFVPGQRYRLRLVNAAMHTHFRFSIDNHDLTVIASDFVPIVPF
TTNNVPIGMGQRYDIIVTANQAPDNYWIRAIPQSFCSDNANSDNIKGVLH
YEGAADNSDPTSTKWDYGDDIQCLDFSLDELVPWLALDADIGGAQMAESD
VDFTPFGDVPLYLWTMGGNALNISWKDPTLQQTFEDPDKMDWKASQGVIE
AAIPNKWTVLVVQTDLPVPHPIHLHGHDFYLLAQGFGQFNPQNVTLKTHN
PPRRDTALMTAATPENGGGGYMVIGFPADNPGVWLIHCHIGFHATEGFAQ
QIVERQSEFNTFFSEDLLENTCDAWDEYAKVNPYGHQYRALAGPYESGI
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain5lm8 Chain A Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5lm8 Structure and function of Aspergillus niger laccase McoG
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H110 H152 H517
Binding residue
(residue number reindexed from 1)		H82 H124 H489
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H108 H110 H152 H154 H448 H451 H453 H515 C516 H517 I518 H521 F526
Catalytic site (residue number reindexed from 1) H80 H82 H124 H126 H420 H423 H425 H487 C488 H489 I490 H493 F498
Enzyme Commision number 1.10.3.2: laccase.
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0052716 hydroquinone:oxygen oxidoreductase activity
Cellular Component
GO:0005575 cellular_component

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:5lm8, PDBe:5lm8, PDBj:5lm8
PDBsum5lm8
PubMed
UniProtA2QS62

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