Structure of PDB 5lm7 Chain A Binding Site BS01

Receptor Information
>5lm7 Chain A (length=428) Species: 83334 (Escherichia coli O157:H7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAMNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEIDVRVQ
IDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIE
SVTFDRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRD
NISLDLGNNAEAVILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVT
RSKPEMLIELFRIEVPEIGEEVIEIKAAARDPGSRAKIAVKTNDKRIDPV
GACVGMRGARVQAVSTELGGERIDIVLWDDNPAQFVINAMAPADVASIVV
DEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGWELNVMTVDDLQAKH
QAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKELLEIEGL
DEPTVEALRERAKNALATIAQAQEESLG
Ligand information
>5lm7 Chain R (length=29) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cucuuuaacauuaagcccugaagaagggc
..............<<<<<.....>>>>>
Receptor-Ligand Complex Structure
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PDB5lm7 Structural basis for lambda N-dependent processive transcription antitermination.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		S232 G249 A250 V252 G253 M254 R255 G256 R258 Q260 R270 I271 I273 I318 R320
Binding residue
(residue number reindexed from 1)		S234 G251 A252 V254 G255 M256 R257 G258 R260 Q262 R272 I273 I275 I320 R322
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003700 DNA-binding transcription factor activity
GO:0003723 RNA binding
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0031554 regulation of termination of DNA-templated transcription
GO:0031564 transcription antitermination

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Molecular Function
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Biological Process
External links
PDB RCSB:5lm7, PDBe:5lm7, PDBj:5lm7
PDBsum5lm7
PubMed28452979
UniProtP0AFF6|NUSA_ECOLI Transcription termination/antitermination protein NusA (Gene Name=nusA)

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