Structure of PDB 5lm5 Chain A Binding Site BS01

Receptor Information
>5lm5 Chain A (length=315) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLNKSGGKKFILELIETVYEEILDLEANLRNGQQTDSTAMWEALHIDDSS
YDVNPFISMLSFDKGIKIMPRIFNFLDKQQKLKILQKIFNELSHLQIIIL
SSYKTTPKPTLTQLKKVDLFQMIILKIIVSFLSNNSNFIEIMGLLLQLIR
NNNVSFLTTSKIGLNLITILISRAALIEISTWNEIYDKLFTSLESKIQLI
FPPREYNDHIMRLQNDKFMDEAYIWAFLASLAASGKLNHQRIIIDEVRDE
IFATINEAETLQKKEKELSVLPQRSQELDTELKSIIYNKEKLYQDLNLFL
NVMGLVYRDGEISEL
Ligand information
>5lm5 Chain C (length=14) Species: 4932 (Saccharomyces cerevisiae) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
SSSPGQLLDILNSK
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5lm5 A unique surface on Pat1 C-terminal domain directly interacts with Dcp2 decapping enzyme and Xrn1 5'-3' mRNA exonuclease in yeast.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Q720 R721 I724 D725 R728 F732 M783 L785 S793 E794
Binding residue
(residue number reindexed from 1)		Q240 R241 I244 D245 R248 F252 M303 L305 S313 E314
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA

View graph for
Biological Process
External links
PDB RCSB:5lm5, PDBe:5lm5, PDBj:5lm5
PDBsum5lm5
PubMed29078363
UniProtP25644|PAT1_YEAST Deadenylation-dependent mRNA-decapping factor PAT1 (Gene Name=PAT1)

[Back to BioLiP]