Structure of PDB 5lm1 Chain A Binding Site BS01

Receptor Information
>5lm1 Chain A (length=339) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLVDNLDAYSHIP
PQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDEL
LEQKFQEAVGISITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLH
VGNLRLLSGPLDQVRAALPTPALSPEDKAVLQNLKRILAKVQEMRDQRVS
LEQQLRELIQKDDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAA
QDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQTLVASYEAYEDLMKKS
QEGRDFYADLESKVAALLERTQSTCQAREAARQQLLDRE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5lm1 Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		A304 D307 K311 G315 F318 D321
Binding residue
(residue number reindexed from 1)		A292 D295 K299 G303 F306 D309
Enzymatic activity
Enzyme Commision number 3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Biological Process
GO:0071985 multivesicular body sorting pathway

View graph for
Biological Process
External links
PDB RCSB:5lm1, PDBe:5lm1, PDBj:5lm1
PDBsum5lm1
PubMed27839950
UniProtQ9H3S7|PTN23_HUMAN Tyrosine-protein phosphatase non-receptor type 23 (Gene Name=PTPN23)

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