Structure of PDB 5lak Chain A Binding Site BS01

Receptor Information
>5lak Chain A (length=303) Species: 1041929 (Cavally virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAASNPSISHIVLEMPVAINPLIKYTTRTSVSSLRGAVVNGYIYIQRHLF
GSKKQEFEACYNNGKGLLNCKNLERSKYDIDSAELIGTLIRIPLHDKHSI
PHISIHPDPLSYNGPVTLYLSRYDTNKDVLCVHTGFMSEGHHDIKTVFGD
CGGMLFDPKGRLLGLHCAGSDDVVFMDTTTGKSNIWTSYKLQHPSEIMIT
LNNEINLPNPANYDFETTKVVYQHPLRNVCATLETLQHLTNKTNAKLPYD
SRLLSDFNITAEQYNQYGYYIDYNNFVNNFNRYTTTTIGTKSFETCIKYG
LMD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5lak Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.
Resolution2.299 Å
Binding residue
(original residue number in PDB)		S52 T148 F150 G151 C153 H168 A170 G171 S172 D173 Y215 D216 E218 T220
Binding residue
(residue number reindexed from 1)		S52 T146 F148 G149 C151 H166 A168 G169 S170 D171 Y213 D214 E216 T218
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:5lak, PDBe:5lak, PDBj:5lak
PDBsum5lak
PubMed31078932
UniProtF8RL29|R1AB_AMV79 Replicase polyprotein 1ab (Gene Name=pp1ab)

[Back to BioLiP]