Structure of PDB 5l7h Chain A Binding Site BS01
Receptor Information
>5l7h Chain A (length=249) Species:
9606
(Homo sapiens) [
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YFSPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWA
KVLPGFKNLPLEDQITLIQYSWMSLLSFALSWRSYKHTNSQFLYFAPDLV
FNEEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKD
GLKSQAAFEEMRTNYIKELRKMVTKSPNSGQSWQRFYQLTKLLDSMHDLV
SDLLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
Ligand information
>5l7h Chain B (length=10) Species:
9606
(Homo sapiens) [
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KSLLQQLLTE
Receptor-Ligand Complex Structure
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PDB
5l7h
Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity.
Resolution
1.84 Å
Binding residue
(original residue number in PDB)
V781 K785 L795 I799 A958 M959 E962
Binding residue
(residue number reindexed from 1)
V47 K51 L61 I65 A223 M224 E227
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5l7h
,
PDBe:5l7h
,
PDBj:5l7h
PDBsum
5l7h
PubMed
27897427
UniProt
P08235
|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)
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