Structure of PDB 5l7g Chain A Binding Site BS01
Receptor Information
>5l7g Chain A (length=247) Species:
9606
(Homo sapiens) [
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SPVMVLENIEPEIVYAGYDSSKPDTAENLLSTLNRLAGKQMIQVVKWAKV
LPGFKNLPLEDQITLIQYSWMSLLSFALSWRSYKHTNSQFLYFAPDLVFN
EEKMHQSAMYELCQGMHQISLQFVRLQLTFEEYTIMKVLLLLSTIPKDGL
KSQAAFEEMRTNYIKELRKMVTKSPNSGQSWQRFYQLTKLLDSMHDLVSD
LLEFCFYTFRESHALKVEFPAMLVEIISDQLPKVESGNAKPLYFHRK
Ligand information
>5l7g Chain B (length=10) Species:
9606
(Homo sapiens) [
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KSLLQQLLTE
Receptor-Ligand Complex Structure
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PDB
5l7g
Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity.
Resolution
2.01 Å
Binding residue
(original residue number in PDB)
V781 K785 L795 I799 I802 A958 M959 E962
Binding residue
(residue number reindexed from 1)
V45 K49 L59 I63 I66 A221 M222 E225
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5l7g
,
PDBe:5l7g
,
PDBj:5l7g
PDBsum
5l7g
PubMed
27897427
UniProt
P08235
|MCR_HUMAN Mineralocorticoid receptor (Gene Name=NR3C2)
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