Structure of PDB 5kvy Chain A Binding Site BS01

Receptor Information
>5kvy Chain A (length=195) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RGSAAQRQGALAIMSRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDS
VTMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIQAQPII
DQLAEEARAFNRIYVASVHQDLSDDDIKSVFEAFGKIKSATLARDPTTGK
HKGYGFIEYEKAQSSQDAVSSMNLFDLGGQYLRVGKAVTPPMPLL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5kvy Unraveling the mechanism of recognition of the 3' splice site of the adenovirus major late promoter intron by the alternative splicing factor PUF60.
Resolution1.95 Å
Binding residue
(original residue number in PDB)		Y132 F172 F174 N199 R204 P205 S206 N207
Binding residue
(residue number reindexed from 1)		Y18 F58 F60 N85 R90 P91 S92 N93
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:5kvy, PDBe:5kvy, PDBj:5kvy
PDBsum5kvy
PubMed33253191
UniProtQ9UHX1|PUF60_HUMAN Poly(U)-binding-splicing factor PUF60 (Gene Name=PUF60)

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