Structure of PDB 5kvm Chain A Binding Site BS01

Receptor Information

>5kvm Chain A (length=355) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PREDFRFCGQRNQTQQSTLHYDQSSEPHIFVWNTEETLTIRAPFLAAPDI
PRFFPEPRGLYHFCLYWSRHTGRLHLRYGKHDYLLSSQASRLLCFQKQEQ
SLKQGAPLIATSVSSWQIPQNTSLPGAPSFIFSFHNAPHKVSHNASVDMC
DLKKELQQLSRYLQHPQKAAKRPTAAFISQQLQSLESKLTSVSFLGDTLS
FEEDRVNATVWKLPPTAGLEDLHIHSQKEEEQSEVQAYSLLLPRAVFQQT
RGRRRDDAKRLLVVDFSSQALFQDKNSSQVLGEKVLGIVVQNTKVTNLSD
PVVLTFQHQPQPKNVTLQCVFWVEDPASSSTGSWSSAGCETVSRDTQTSC
LCNHL

Ligand information

>5kvm Chain B (length=9) Species: 10090 (Mus musculus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

TYFAVLMVS

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5kvm Structural Basis for Regulation of GPR56/ADGRG1 by Its Alternatively Spliced Extracellular Domains.
Resolution	2.449 Å
Binding residue (original residue number in PDB)	F293 F299 Q306 V307 L308 V312 L313 G314 I315 F333 N341 V342 T343 L344 Q345 V347 F348 W361 L382
Binding residue (residue number reindexed from 1)	F266 F272 Q279 V280 L281 V285 L286 G287 I288 F306 N314 V315 T316 L317 Q318 V320 F321 W334 L355

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0004930	G protein-coupled receptor activity

	Biological Process
GO:0007186	G protein-coupled receptor signaling pathway

	Cellular Component
GO:0016020	membrane

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Molecular Function

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Biological Process

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Cellular Component

External links

PDB	RCSB:5kvm, PDBe:5kvm, PDBj:5kvm
PDBsum	5kvm
PubMed	27657451
UniProt	Q8K209\|AGRG1_MOUSE Adhesion G-protein coupled receptor G1 (Gene Name=Adgrg1)

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